Their stay at the summit may be a brief one - with nearest rivals Liverpool playing third-placed Chelsea in Saturday's late game - but the outcome of this match was rarely in doubt.
Sterling broke the deadlock after 29 minutes, sliding home Leroy Sane's cross after a swift counter-attack opened up the Seagulls defence for the first time.
City continued to dominate and Aguero made sure of the points on 65 minutes, firing home from a Sterling pass to finish a move he started.
Tags:
Premier legue